COVID-19 Vaccines for Moderately to Severely Immunocompromised People
Commonly Questioned Questions
How long soon after receiving my original COVID-19 vaccines can I get an additional dose?
CDC recommends the additional dose of an mRNA COVID-19 vaccine be administered at minimum 4 months soon after a second dose of Pfizer-BioNTech COVID-19 vaccine or Moderna COVID-19 vaccine.
Can you mix and match the vaccines?
For individuals who gained possibly Pfizer-BioNTech or Moderna’s COVID-19 vaccine series, a 3rd dose of the same mRNA vaccine really should be applied. A individual really should not acquire far more than three mRNA vaccine doses. If the mRNA vaccine solution given for the 1st two doses is not readily available or is unidentified, possibly mRNA COVID-19 vaccine solution may possibly be administered.
What really should immunocompromised individuals who gained the J&J/Janssen vaccine do?
The FDA’s latest EUA modification only applies to mRNA COVID-19 vaccines, as does CDC’s recommendation.
Emerging details have shown that immunocompromised individuals who have very low or no defense adhering to two doses of mRNA COVID-19 vaccines may possibly have an improved response soon after an additional dose of the same vaccine. There is not ample details at this time to figure out no matter if immunocompromised individuals who gained the Johnson & Johnson’s Janssen COVID-19 vaccine also have an improved antibody response adhering to an additional dose of the same vaccine.
What are the advantages of individuals acquiring an additional vaccine dose?
An additional dose may possibly avert really serious and probably existence-threatening COVID-19 in individuals who may possibly not have responded to their original vaccine series. In ongoing medical trials, the mRNA COVID-19 vaccines (Pfizer-BioNTech or Moderna) have been demonstrated to avert COVID-19 adhering to the two-dose series. Minimal details suggests that immunocompromised individuals who have very low or no defense soon after two doses of mRNA vaccines may possibly have an improved response soon after an additional dose of the same vaccine.
What are the challenges of vaccinating individuals with an additional dose?
There is minimal details about the challenges of acquiring an additional dose of vaccine, and the safety, efficacy, and benefit of additional doses of COVID-19 vaccine in immunocompromised individuals continues to be evaluated. So considerably, reactions documented soon after the 3rd mRNA dose were being related to that of the two-dose series: fatigue and agony at injection web site were being the most generally documented side consequences, and general, most symptoms were being mild to average.
Nevertheless, as with the two-dose series, really serious side consequences are scarce, but may possibly happen.