What is an immunofixation (IFE) blood examination?

An immunofixation blood examination, also known as protein electrophoresis, measures particular proteins in the blood. Proteins engage in many essential roles, which include providing electrical power for the overall body, rebuilding muscle groups, and supporting the immune system.

There are two key varieties of proteins in the blood: albumin and globulin. The examination separates these proteins into subgroups based mostly on their dimensions and electrical charge. The subgroups are:

  • Albumin
  • Alpha-1 globulin
  • Alpha-2 globulin
  • Beta globulin
  • Gamma globulin

Measuring the proteins in just about every subgroup can aid diagnose a wide range of conditions.

Other names: serum protein electrophoresis, (SPEP), protein electrophoresis, SPE, immunofixation electrophoresis, IFE, serum immunofixation